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Insulin Preconditioning Elevates p-Akt and Cardiac Contractility after Reperfusion in the Isolated Ischemic Rat Heart
Insulin induces cardioprotection partly via an antiapoptotic effect. However, the optimal timing of insulin administration for the best quality cardioprotection remains unclear. We tested the hypothesis that insulin administered prior to ischemia provides better cardioprotection than insulin adminis...
Autores principales: | Sato, Tamaki, Sato, Hiroaki, Oguchi, Takeshi, Fukushima, Hisashi, Carvalho, George, Lattermann, Ralph, Matsukawa, Takashi, Schricker, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147204/ https://www.ncbi.nlm.nih.gov/pubmed/25197648 http://dx.doi.org/10.1155/2014/536510 |
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