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Delay Differential Model for Tumour-Immune Response with Chemoimmunotherapy and Optimal Control

We present a delay differential model with optimal control that describes the interactions of the tumour cells and immune response cells with external therapy. The intracellular delay is incorporated into the model to justify the time required to stimulate the effector cells. The optimal control var...

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Detalles Bibliográficos
Autores principales: Rihan, F. A., Abdelrahman, D. H., Al-Maskari, F., Ibrahim, F., Abdeen, M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147205/
https://www.ncbi.nlm.nih.gov/pubmed/25197319
http://dx.doi.org/10.1155/2014/982978