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Delay Differential Model for Tumour-Immune Response with Chemoimmunotherapy and Optimal Control
We present a delay differential model with optimal control that describes the interactions of the tumour cells and immune response cells with external therapy. The intracellular delay is incorporated into the model to justify the time required to stimulate the effector cells. The optimal control var...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147205/ https://www.ncbi.nlm.nih.gov/pubmed/25197319 http://dx.doi.org/10.1155/2014/982978 |