Aromatic Amino Acid Mutagenesis at the Substrate Binding Pocket of Yarrowia lipolytica Lipase Lip2 Affects Its Activity and Thermostability

The lipase2 from Yarrowia lipolytica (YLLip2) is a yeast lipase exhibiting high homologous to filamentous fungal lipase family. Though its crystal structure has been resolved, its structure-function relationship has rarely been reported. By contrast, there are two amino acid residues (V94 and I100)...

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Detalles Bibliográficos
Autores principales: Wang, Guilong, Liu, Zimin, Xu, Li, Yan, Yunjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147282/
https://www.ncbi.nlm.nih.gov/pubmed/25197700
http://dx.doi.org/10.1155/2014/382581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147282/
https://www.ncbi.nlm.nih.gov/pubmed/25197700
http://dx.doi.org/10.1155/2014/382581

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