Identification of a ternary protein-complex as a therapeutic target for K-Ras-dependent colon cancer

A cancer phenotype is driven by several proteins and targeting a cluster of functionally interdependent molecules should be more effective for therapeutic intervention. This is specifically important for Ras-dependent cancer, as mutated (MT) Ras is non-druggable and targeting its interaction with ef...

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Detalles Bibliográficos
Autores principales: Qi, Xiaomei, Xie, Congying, Hou, Songwang, Li, Gang, Yin, Ning, Dong, Lei, Lepp, Adrienne, Chesnik, Marla A., Mirza, Shama P., Szabo, Aniko, Tsai, Susan, Basir, Zainab, Wu, Shixiu, Chen, Guan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147322/
https://www.ncbi.nlm.nih.gov/pubmed/24962213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147322/
https://www.ncbi.nlm.nih.gov/pubmed/24962213

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