XIAP inhibitors induce differentiation and impair clonogenic capacity of acute myeloid leukemia stem cells

Acute myeloid leukemia (AML) is a neoplasia characterized by the rapid expansion of immature myeloid blasts in the bone marrow, and marked by poor prognosis and frequent relapse. As such, new therapeutic approaches are required for remission induction and prevention of relapse. Due to the higher che...

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Detalles Bibliográficos
Autores principales: Moreno-Martínez, Daniel, Nomdedeu, Meritxell, Lara-Castillo, María Carmen, Etxabe, Amaia, Pratcorona, Marta, Tesi, Niccolò, Díaz-Beyá, Marina, Rozman, María, Montserrat, Emili, Urbano-Ispizua, Álvaro, Esteve, Jordi, Risueño, Ruth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147327/
https://www.ncbi.nlm.nih.gov/pubmed/24952669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147327/
https://www.ncbi.nlm.nih.gov/pubmed/24952669

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