Cargando…

Stiff substrates enhance cultured neuronal network activity

The mechanical property of extracellular matrix and cell-supporting substrates is known to modulate neuronal growth, differentiation, extension and branching. Here we show that substrate stiffness is an important microenvironmental cue, to which mouse hippocampal neurons respond and integrate into s...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Quan-You, Zhang, Yan-Yan, Xie, Jing, Li, Chen-Xu, Chen, Wei-Yi, Liu, Bai-Lin, Wu, Xiao-an, Li, Shu-Na, Huo, Bo, Jiang, Lin-Hua, Zhao, Hu-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147369/
https://www.ncbi.nlm.nih.gov/pubmed/25163607
http://dx.doi.org/10.1038/srep06215