Metformin directly acts on mitochondria to alter cellular bioenergetics

BACKGROUND: Metformin is widely used in the treatment of diabetes, and there is interest in ‘repurposing’ the drug for cancer prevention or treatment. However, the mechanism underlying the metabolic effects of metformin remains poorly understood. METHODS: We performed respirometry and stable isotope...

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Detalles Bibliográficos
Autores principales: Andrzejewski, Sylvia, Gravel, Simon-Pierre, Pollak, Michael, St-Pierre, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147388/
https://www.ncbi.nlm.nih.gov/pubmed/25184038
http://dx.doi.org/10.1186/2049-3002-2-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147388/
https://www.ncbi.nlm.nih.gov/pubmed/25184038
http://dx.doi.org/10.1186/2049-3002-2-12

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