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Metformin directly acts on mitochondria to alter cellular bioenergetics
BACKGROUND: Metformin is widely used in the treatment of diabetes, and there is interest in ‘repurposing’ the drug for cancer prevention or treatment. However, the mechanism underlying the metabolic effects of metformin remains poorly understood. METHODS: We performed respirometry and stable isotope...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147388/ https://www.ncbi.nlm.nih.gov/pubmed/25184038 http://dx.doi.org/10.1186/2049-3002-2-12 |