Synthesis and Analgesic Effects of μ-TRTX-Hhn1b on Models of Inflammatory and Neuropathic Pain

μ-TRTX-Hhn1b (HNTX-IV) is a 35-amino acid peptide isolated from the venom of the spider, Ornithoctonus hainana. It inhibits voltage-gated sodium channel Nav1.7, which has been considered as a therapeutic target for pain. The goal of the present study is to elucidate the analgesic effects of syntheti...

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Detalles Bibliográficos
Autores principales: Liu, Yu, Tang, Jianguang, Zhang, Yunxiao, Xun, Xiaohong, Tang, Dongfang, Peng, Dezheng, Yi, Jianming, Liu, Zhonghua, Shi, Xiaoliu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147587/
https://www.ncbi.nlm.nih.gov/pubmed/25123556
http://dx.doi.org/10.3390/toxins6082363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147587/
https://www.ncbi.nlm.nih.gov/pubmed/25123556
http://dx.doi.org/10.3390/toxins6082363

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