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Methylation analysis of the phosphates and tensin homologue on chromosome 10 gene (PTEN) in multiple myeloma

BACKGROUND: Aberrant DNA methylation of promoter region CpG islands is an alternative mechanism that leads to genetic defects in the inactivation of tumor suppressor genes during myelomagenesis. The aim of this study was to examine the promoter methylation status of the phosphates and tensin homolog...

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Detalles Bibliográficos
Autores principales: Piras, Giovanna, Monne, Maria, Palmas, Angelo D, Calvisi, Anna, Asproni, Rosanna, Vacca, Francesco, Pilo, Laura, Gabbas, Attilio, Latte, Giancarlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147879/
https://www.ncbi.nlm.nih.gov/pubmed/25170349
http://dx.doi.org/10.1186/1868-7083-6-16