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Methylation analysis of the phosphates and tensin homologue on chromosome 10 gene (PTEN) in multiple myeloma
BACKGROUND: Aberrant DNA methylation of promoter region CpG islands is an alternative mechanism that leads to genetic defects in the inactivation of tumor suppressor genes during myelomagenesis. The aim of this study was to examine the promoter methylation status of the phosphates and tensin homolog...
Autores principales: | Piras, Giovanna, Monne, Maria, Palmas, Angelo D, Calvisi, Anna, Asproni, Rosanna, Vacca, Francesco, Pilo, Laura, Gabbas, Attilio, Latte, Giancarlo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147879/ https://www.ncbi.nlm.nih.gov/pubmed/25170349 http://dx.doi.org/10.1186/1868-7083-6-16 |
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