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Efficient RNA isoform identification and quantification from RNA-Seq data with network flows

Motivation: Several state-of-the-art methods for isoform identification and quantification are based on [Formula: see text]-regularized regression, such as the Lasso. However, explicitly listing the—possibly exponentially—large set of candidate transcripts is intractable for genes with many exons. F...

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Detalles Bibliográficos
Autores principales: Bernard, Elsa, Jacob, Laurent, Mairal, Julien, Vert, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147886/
https://www.ncbi.nlm.nih.gov/pubmed/24813214
http://dx.doi.org/10.1093/bioinformatics/btu317