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Modeling DNA methylation dynamics with approaches from phylogenetics

Motivation: Methylation of CpG dinucleotides is a prevalent epigenetic modification that is required for proper development in vertebrates. Genome-wide DNA methylation assays have become increasingly common, and this has enabled characterization of DNA methylation in distinct stages across different...

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Detalles Bibliográficos
Autores principales: Capra, John A., Kostka, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147898/
https://www.ncbi.nlm.nih.gov/pubmed/25161227
http://dx.doi.org/10.1093/bioinformatics/btu445