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Identification of structural features in chemicals associated with cancer drug response: a systematic data-driven analysis
Motivation: Analysis of relationships of drug structure to biological response is key to understanding off-target and unexpected drug effects, and for developing hypotheses on how to tailor drug therapies. New methods are required for integrated analyses of a large number of chemical features of dru...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147909/ https://www.ncbi.nlm.nih.gov/pubmed/25161239 http://dx.doi.org/10.1093/bioinformatics/btu456 |