Cargando…

CRISPRstrand: predicting repeat orientations to determine the crRNA-encoding strand at CRISPR loci

Motivation: The discovery of CRISPR-Cas systems almost 20 years ago rapidly changed our perception of the bacterial and archaeal immune systems. CRISPR loci consist of several repetitive DNA sequences called repeats, inter-spaced by stretches of variable length sequences called spacers. This CRISPR...

Descripción completa

Detalles Bibliográficos
Autores principales: Alkhnbashi, Omer S., Costa, Fabrizio, Shah, Shiraz A., Garrett, Roger A., Saunders, Sita J., Backofen, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147912/
https://www.ncbi.nlm.nih.gov/pubmed/25161238
http://dx.doi.org/10.1093/bioinformatics/btu459