OncodriveROLE classifies cancer driver genes in loss of function and activating mode of action

Motivation: Several computational methods have been developed to identify cancer drivers genes—genes responsible for cancer development upon specific alterations. These alterations can cause the loss of function (LoF) of the gene product, for instance, in tumor suppressors, or increase or change its...

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Detalles Bibliográficos
Autores principales: Schroeder, Michael P., Rubio-Perez, Carlota, Tamborero, David, Gonzalez-Perez, Abel, Lopez-Bigas, Nuria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Eccb 2014 Proceedings Papers Committee
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147920/
https://www.ncbi.nlm.nih.gov/pubmed/25161246
http://dx.doi.org/10.1093/bioinformatics/btu467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147920/
https://www.ncbi.nlm.nih.gov/pubmed/25161246
http://dx.doi.org/10.1093/bioinformatics/btu467

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