Cargando…
OncodriveROLE classifies cancer driver genes in loss of function and activating mode of action
Motivation: Several computational methods have been developed to identify cancer drivers genes—genes responsible for cancer development upon specific alterations. These alterations can cause the loss of function (LoF) of the gene product, for instance, in tumor suppressors, or increase or change its...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147920/ https://www.ncbi.nlm.nih.gov/pubmed/25161246 http://dx.doi.org/10.1093/bioinformatics/btu467 |