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Unveiling new biological relationships using shared hits of chemical screening assay pairs

Motivation: Although the integration and analysis of the activity of small molecules across multiple chemical screens is a common approach to determine the specificity and toxicity of hits, the suitability of these approaches to reveal novel biological information is less explored. Here, we test the...

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Detalles Bibliográficos
Autores principales: Liu, Xueping, Campillos, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147921/
https://www.ncbi.nlm.nih.gov/pubmed/25161250
http://dx.doi.org/10.1093/bioinformatics/btu468