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Investigation of IL-23 (p19, p40) and IL-23R identifies nuclear expression of IL-23 p19 as a favorable prognostic factor in colorectal cancer: a retrospective multicenter study of 675 patients

IL-23 is a heterodimeric cytokine involved in inflammatory diseases; its role in cancer progression is controversial. Here we analyse the expression of IL-23 subunits (p40 and p19) and IL-23R in colorectal cancer with regard to disease progression, clinical-pathological and molecular aspects. Immuno...

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Detalles Bibliográficos
Autores principales: Helbling, Melina, Lukesch, Anne, Haimovici, Aladin, Karamitopoulou, Eva, Berger, Martin D., Hädrich, Marion, Mallaev, Makhmud, Schnüriger, Beat, Koelzer, Viktor H., Dawson, Heather, Borner, Markus, Langer, Rupert, Rosenberg, Robert, Nitsche, Ulrich, Inderbitzin, Daniel, Lugli, Alessandro, Tschan, Mario P., Zlobec, Inti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148090/
https://www.ncbi.nlm.nih.gov/pubmed/25015728