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Capturing the metabolomic diversity of KRAS mutants in non-small-cell lung cancer cells

In non-small-cell lung cancer (NSCLC), one-fifth of patients have KRAS mutations, which are considered a negative predictive factor to first-line therapy. Evidence is emerging that not all KRAS mutations have the same biological activities and possible remodeling of cell metabolism by KRAS activatio...

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Detalles Bibliográficos
Autores principales: Brunelli, Laura, Caiola, Elisa, Marabese, Mirko, Broggini, Massimo, Pastorelli, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148094/
https://www.ncbi.nlm.nih.gov/pubmed/24952473