Nicotine and oxidative stress induced exomic variations are concordant and overrepresented in cancer-associated genes

Although the connection between cancer and cigarette smoke is well established, nicotine is not characterized as a carcinogen. Here, we used exome sequencing to identify nicotine and oxidative stress-induced somatic mutations in normal human epithelial cells and its correlation with cancer. We ident...

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Detalles Bibliográficos
Autores principales: Bavarva, Jasmin H., Tae, Hongseok, McIver, Lauren, Garner, Harold R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148099/
https://www.ncbi.nlm.nih.gov/pubmed/24947164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148099/
https://www.ncbi.nlm.nih.gov/pubmed/24947164

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