Lapatinib induces autophagic cell death and inhibits growth of human hepatocellular carcinoma

Lapatinib, an orally adminstered small-molecule tyrosine kinase inhibitor targeting epidermal growth factor receptors (EGFR) and Her2/Neu, has been widely accepted in the treatment of breast cancer. In this study, we found that lapatinib induced cytotoxicity in human hepatoma Huh7, HepG2 and HA22T c...

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Detalles Bibliográficos
Autores principales: Chen, Yu-Jen, Chi, Chih-Wen, Su, Wen-Chi, Huang, Huey-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148104/
https://www.ncbi.nlm.nih.gov/pubmed/24947784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148104/
https://www.ncbi.nlm.nih.gov/pubmed/24947784

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