Afatinib and its encapsulated polymeric micelles inhibits HER2-overexpressed colorectal tumor cell growth in vitro and in vivo

Colorectal cancer (CRC) is known as a common malignant neoplasm worldwide. The role of EGFR/HER2 in CRC is unclear. Afatinib is an irreversible EGFR/HER2 inhibitor. There were few studies of afatinib on CRC. Here, we investigated the protein levels/expressions of HER2 in sera and tumors from CRC pat...

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Detalles Bibliográficos
Autores principales: Guan, Siao-Syun, Chang, Jungshan, Cheng, Chun-Chia, Luo, Tsai-Yueh, Ho, Ai-Sheng, Wang, Chia-Chi, Wu, Cheng-Tien, Liu, Shing-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148106/
https://www.ncbi.nlm.nih.gov/pubmed/24947902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148106/
https://www.ncbi.nlm.nih.gov/pubmed/24947902

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