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GCIP functions as a tumor suppressor in non-small cell lung cancer by suppressing Id1-mediated tumor promotion

Grap2 and cyclin D1 interacting protein (GCIP) has been recognized as a putative tumor suppressor, but the molecular mechanisms underlying its anti-tumor properties remain undefined. Here, we report that GCIP is frequently downregulated in non-small cell lung cancer (NSCLC) tissues. Binding assays i...

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Detalles Bibliográficos
Autores principales: Chen, Kuan-yu, Chen, Chao-chung, Tseng, Yau-lin, Chang, Yi-chien, Chang, Ming-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148118/
https://www.ncbi.nlm.nih.gov/pubmed/24970809