The MAPK pathway as an apoptosis enhancer in melanoma

Inhibition of RAF/MEK/ERK signaling is beneficial for many patients with BRAF(V600E)–mutated melanoma. However, primary and secondary resistances restrict long-lasting therapy success. Combination therapies are therefore urgently needed. Here, we evaluate the cellular effect of combining a MEK inhib...

Descripción completa

Detalles Bibliográficos
Autores principales: Haydn, Johannes M., Hufnagel, Anita, Grimm, Johannes, Maurus, Katja, Schartl, Manfred, Meierjohann, Svenja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148120/
https://www.ncbi.nlm.nih.gov/pubmed/24970815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148120/
https://www.ncbi.nlm.nih.gov/pubmed/24970815

Ejemplares similares