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The MAPK pathway as an apoptosis enhancer in melanoma

Inhibition of RAF/MEK/ERK signaling is beneficial for many patients with BRAF(V600E)–mutated melanoma. However, primary and secondary resistances restrict long-lasting therapy success. Combination therapies are therefore urgently needed. Here, we evaluate the cellular effect of combining a MEK inhib...

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Detalles Bibliográficos
Autores principales:	Haydn, Johannes M., Hufnagel, Anita, Grimm, Johannes, Maurus, Katja, Schartl, Manfred, Meierjohann, Svenja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148120/ https://www.ncbi.nlm.nih.gov/pubmed/24970815

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