Niraparib (MK-4827), a novel poly(ADP-Ribose) polymerase inhibitor, radiosensitizes human lung and breast cancer cells

The aim of this study was to assess niraparib (MK-4827), a novel poly(ADP-Ribose) polymerase (PARP) inhibitor, for its ability to radiosensitize human tumor cells. Human tumor cells derived from lung, breast and prostate cancers were tested for radiosensitization by niraparib using clonogenic surviv...

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Detalles Bibliográficos
Autores principales: Bridges, Kathleen A., Toniatti, Carlo, Buser, Carolyn A., Liu, Huifeng, Buchholz, Thomas A., Meyn, Raymond E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148123/
https://www.ncbi.nlm.nih.gov/pubmed/24970803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148123/
https://www.ncbi.nlm.nih.gov/pubmed/24970803

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