Structural Study of the RIPoptosome Core Reveals a Helical Assembly for Kinase Recruitment

[Image: see text] Receptor interaction protein kinase 1 (RIP1) is a molecular cell-fate switch. RIP1, together with Fas-associated protein with death domain (FADD) and caspase-8, forms the RIPoptosome that activates apoptosis. RIP1 also associates with RIP3 to form the necrosome that triggers necrop...

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Detalles Bibliográficos
Autores principales: Jang, Tae-ho, Zheng, Chao, Li, Jixi, Richards, Claire, Hsiao, Yu-Shan, Walz, Thomas, Wu, Hao, Park, Hyun Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148139/
https://www.ncbi.nlm.nih.gov/pubmed/25119434
http://dx.doi.org/10.1021/bi500585u

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148139/
https://www.ncbi.nlm.nih.gov/pubmed/25119434
http://dx.doi.org/10.1021/bi500585u

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