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Interaction of Daptomycin with Lipid Bilayers: A Lipid Extracting Effect

[Image: see text] Daptomycin is the first approved member of a new structural class of antibiotics, the cyclic lipopeptides. The peptide interacts with the lipid matrix of cell membranes, inducing permeability of the membrane to ions, but its molecular mechanism has been a puzzle. Unlike the ubiquit...

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Detalles Bibliográficos
Autores principales: Chen, Yen-Fei, Sun, Tzu-Lin, Sun, Yen, Huang, Huey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148140/
https://www.ncbi.nlm.nih.gov/pubmed/25093761
http://dx.doi.org/10.1021/bi500779g