Cargando…

Ultrafast Water Dynamics at the Interface of the Polymerase–DNA Binding Complex

[Image: see text] DNA polymerases slide on DNA during replication, and the interface must be mobile for various conformational changes. The role of lubricant interfacial water is not understood. In this report, we systematically characterize the water dynamics at the interface and in the active site...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Yi, Qin, Yangzhong, Ding, Qing, Bakhtina, Marina, Wang, Lijuan, Tsai, Ming-Daw, Zhong, Dongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148141/
https://www.ncbi.nlm.nih.gov/pubmed/25105470
http://dx.doi.org/10.1021/bi500810a