Bioengineered Vaults: Self-Assembling Protein Shell–Lipophilic Core Nanoparticles for Drug Delivery

[Image: see text] We report a novel approach to a new class of bioengineered, monodispersed, self-assembling vault nanoparticles consisting of a protein shell exterior with a lipophilic core interior designed for drug and probe delivery. Recombinant vaults were engineered to contain a small amphipat...

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Detalles Bibliográficos
Autores principales: Buehler, Daniel C., Marsden, Matthew D., Shen, Sean, Toso, Daniel B., Wu, Xiaomeng, Loo, Joseph A., Zhou, Z. Hong, Kickhoefer, Valerie A., Wender, Paul A., Zack, Jerome A., Rome, Leonard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148163/
https://www.ncbi.nlm.nih.gov/pubmed/25061969
http://dx.doi.org/10.1021/nn5002694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148163/
https://www.ncbi.nlm.nih.gov/pubmed/25061969
http://dx.doi.org/10.1021/nn5002694

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