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14,15-Epoxyeicosa-5,8,11-trienoic Acid (14,15-EET) Surrogates: Carboxylate Modifications

[Image: see text] The cytochrome P450 eicosanoid 14,15-epoxyeicosa-5,8,11-trienoic acid (14,15-EET) is a powerful endogenous autacoid that has been ascribed an impressive array of physiologic functions including regulation of blood pressure. Because 14,15-EET is chemically and metabolically labile,...

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Detalles Bibliográficos
Autores principales: Falck, John R., Koduru, Sreenivasulu Reddy, Mohapatra, Seetaram, Manne, Rajkumar, Atcha, Raju, Manthati, Vijaya L., Capdevila, Jorge H., Christian, Sarah, Imig, John D., Campbell, William B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148164/
https://www.ncbi.nlm.nih.gov/pubmed/25119815
http://dx.doi.org/10.1021/jm500262m