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Niemann-Pick C1 Affects the Gene Delivery Efficacy of Degradable Polymeric Nanoparticles

[Image: see text] Despite intensive research effort, the rational design of improved nanoparticulate drug carriers remains challenging, in part due to a limited understanding of the determinants of nanoparticle entry and transport in target cells. Recent studies have shown that Niemann-Pick C1 (NPC1...

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Detalles Bibliográficos
Autores principales: Eltoukhy, Ahmed A., Sahay, Gaurav, Cunningham, James M., Anderson, Daniel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148171/
https://www.ncbi.nlm.nih.gov/pubmed/25010491
http://dx.doi.org/10.1021/nn501630h