A marked paucity of granule cells in the developing cerebellum of the Npc1(−/−) mouse is corrected by a single injection of hydroxypropyl-β-cyclodextrin

In this study we show that postnatal development of cerebellar granule neurons (GNs) is defective in Npc1(−/−) mice. Compared to age-matched wild-type littermates, there is an accelerated disappearance of the external granule layer (EGL) in these mice. This is due to a premature exit from the cell c...

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Detalles Bibliográficos
Autores principales: Nusca, S., Canterini, S., Palladino, G., Bruno, F., Mangia, F., Erickson, R.P., Fiorenza, M.T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148175/
https://www.ncbi.nlm.nih.gov/pubmed/24969023
http://dx.doi.org/10.1016/j.nbd.2014.06.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148175/
https://www.ncbi.nlm.nih.gov/pubmed/24969023
http://dx.doi.org/10.1016/j.nbd.2014.06.012

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