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Clinical pharmacology and regulatory consequences of GnRH analogues in prostate cancer

INTRODUCTION: GnRH (gonadotropin-releasing hormone) analogues are long-term known to be safe and effective in the clinical management of hormone-dependent advanced prostate cancer. However, their unusual mechanism of action of de-sensitizing pituitary receptors makes generic market entry challenging...

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Detalles Bibliográficos
Autores principales: Eckstein, Niels, Haas, Bodo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148177/
https://www.ncbi.nlm.nih.gov/pubmed/24756149
http://dx.doi.org/10.1007/s00228-014-1682-1