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Clinical pharmacology and regulatory consequences of GnRH analogues in prostate cancer
INTRODUCTION: GnRH (gonadotropin-releasing hormone) analogues are long-term known to be safe and effective in the clinical management of hormone-dependent advanced prostate cancer. However, their unusual mechanism of action of de-sensitizing pituitary receptors makes generic market entry challenging...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Berlin Heidelberg
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148177/ https://www.ncbi.nlm.nih.gov/pubmed/24756149 http://dx.doi.org/10.1007/s00228-014-1682-1 |