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The role of pro-inflammatory S100A9 in Alzheimer’s disease amyloid-neuroinflammatory cascade

Pro-inflammatory S100A9 protein is increasingly recognized as an important contributor to inflammation-related neurodegeneration. Here, we provide insights into S100A9 specific mechanisms of action in Alzheimer’s disease (AD). Due to its inherent amyloidogenicity S100A9 contributes to amyloid plaque...

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Detalles Bibliográficos
Autores principales: Wang, Chao, Klechikov, Alexey G., Gharibyan, Anna L., Wärmländer, Sebastian K. T. S., Jarvet, Jüri, Zhao, Lina, Jia, Xueen, Shankar, S. K., Olofsson, Anders, Brännström, Thomas, Mu, Yuguang, Gräslund, Astrid, Morozova-Roche, Ludmilla A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148179/
https://www.ncbi.nlm.nih.gov/pubmed/24240735
http://dx.doi.org/10.1007/s00401-013-1208-4