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Protein Surface Softness Is the Origin of Enzyme Cold-Adaptation of Trypsin

Life has effectively colonized most of our planet and extremophilic organisms require specialized enzymes to survive under harsh conditions. Cold-loving organisms (psychrophiles) express heat-labile enzymes that possess a high specific activity and catalytic efficiency at low temperatures. A remarka...

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Detalles Bibliográficos
Autores principales: Isaksen, Geir Villy, Åqvist, Johan, Brandsdal, Bjørn Olav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148182/
https://www.ncbi.nlm.nih.gov/pubmed/25165981
http://dx.doi.org/10.1371/journal.pcbi.1003813