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Protein Surface Softness Is the Origin of Enzyme Cold-Adaptation of Trypsin
Life has effectively colonized most of our planet and extremophilic organisms require specialized enzymes to survive under harsh conditions. Cold-loving organisms (psychrophiles) express heat-labile enzymes that possess a high specific activity and catalytic efficiency at low temperatures. A remarka...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148182/ https://www.ncbi.nlm.nih.gov/pubmed/25165981 http://dx.doi.org/10.1371/journal.pcbi.1003813 |