Ku-Mediated Coupling of DNA Cleavage and Repair during Programmed Genome Rearrangements in the Ciliate Paramecium tetraurelia

During somatic differentiation, physiological DNA double-strand breaks (DSB) can drive programmed genome rearrangements (PGR), during which DSB repair pathways are mobilized to safeguard genome integrity. Because of their unique nuclear dimorphism, ciliates are powerful unicellular eukaryotic models...

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Detalles Bibliográficos
Autores principales: Marmignon, Antoine, Bischerour, Julien, Silve, Aude, Fojcik, Clémentine, Dubois, Emeline, Arnaiz, Olivier, Kapusta, Aurélie, Malinsky, Sophie, Bétermier, Mireille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148214/
https://www.ncbi.nlm.nih.gov/pubmed/25166013
http://dx.doi.org/10.1371/journal.pgen.1004552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148214/
https://www.ncbi.nlm.nih.gov/pubmed/25166013
http://dx.doi.org/10.1371/journal.pgen.1004552

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