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Actin-associated protein palladin promotes tumor cell invasion by linking extracellular matrix degradation to cell cytoskeleton

Basal-like breast carcinomas, characterized by unfavorable prognosis and frequent metastases, are associated with epithelial-to-mesenchymal transition. During this process, cancer cells undergo cytoskeletal reorganization and up-regulate membrane-type 1 matrix metalloproteinase (MT1-MMP; MMP14), whi...

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Detalles Bibliográficos
Autores principales: von Nandelstadh, Pernilla, Gucciardo, Erika, Lohi, Jouko, Li, Rui, Sugiyama, Nami, Carpen, Olli, Lehti, Kaisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148246/
https://www.ncbi.nlm.nih.gov/pubmed/24989798
http://dx.doi.org/10.1091/mbc.E13-11-0667