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Ena/VASP regulates mDia2-initiated filopodial length, dynamics, and function

Filopodia are long plasma membrane extensions involved in the formation of adhesive, contractile, and protrusive actin-based structures in spreading and migrating cells. Whether filopodia formed by different molecular mechanisms equally support these cellular functions is unresolved. We used Enabled...

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Detalles Bibliográficos
Autores principales: Barzik, Melanie, McClain, Leslie M., Gupton, Stephanie L., Gertler, Frank B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148250/
https://www.ncbi.nlm.nih.gov/pubmed/24989797
http://dx.doi.org/10.1091/mbc.E14-02-0712