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Tumor Suppressor MicroRNA-27a in Colorectal Carcinogenesis and Progression by Targeting SGPP1 and Smad2

The aberrant expression of microRNAs (miRNAs) is associated with colorectal carcinogenesis, but the underlying mechanisms are not clear. This study showed that the miRNA-27a (miR-27a) was significantly reduced in colorectal cancer tissues and colorectal cancer cell lines, and that the reduced miR-27...

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Detalles Bibliográficos
Autores principales: Bao, Yonghua, Chen, Zhiguo, Guo, Yongchen, Feng, Yansheng, Li, Zexin, Han, Wenliang, Wang, Jianguo, Zhao, Weixing, Jiao, Yunjuan, Li, Kai, Wang, Qian, Wang, Jiaqi, Zhang, Huijuan, Wang, Liang, Yang, Wancai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148394/
https://www.ncbi.nlm.nih.gov/pubmed/25166914
http://dx.doi.org/10.1371/journal.pone.0105991