Primary Seronegative but Molecularly Evident Hepadnaviral Infection Engages Liver and Induces Hepatocarcinoma in the Woodchuck Model of Hepatitis B

Hepadnavirus at very low doses establishes in woodchucks asymptomatic, serologically undetectable but molecularly evident persistent infection. This primary occult infection (POI) preferentially engages the immune system and initiates virus-specific T cell response in the absence of antiviral antibo...

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Detalles Bibliográficos
Autores principales: Mulrooney-Cousins, Patricia M., Chauhan, Ranjit, Churchill, Norma D., Michalak, Tomasz I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148403/
https://www.ncbi.nlm.nih.gov/pubmed/25165821
http://dx.doi.org/10.1371/journal.ppat.1004332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148403/
https://www.ncbi.nlm.nih.gov/pubmed/25165821
http://dx.doi.org/10.1371/journal.ppat.1004332

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