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Human Cytomegalovirus pUL79 Is an Elongation Factor of RNA Polymerase II for Viral Gene Transcription

In this study, we have identified a unique mechanism in which human cytomegalovirus (HCMV) protein pUL79 acts as an elongation factor to direct cellular RNA polymerase II for viral transcription during late times of infection. We and others previously reported that pUL79 and its homologues are requi...

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Detalles Bibliográficos
Autores principales: Perng, Yi-Chieh, Campbell, Jessica A., Lenschow, Deborah J., Yu, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148446/
https://www.ncbi.nlm.nih.gov/pubmed/25166009
http://dx.doi.org/10.1371/journal.ppat.1004350