The phosphorylation of Hsp20 enhances its association with amyloid-β to increase protection against neuronal cell death

Up-regulation of Hsp20 protein levels in response to amyloid fibril formation is considered a key protective response against the onset of Alzheimer's disease (AD). Indeed, the physical interaction between Hsp20 and Aβ is known to prevent Aβ oligomerisation and protects neuronal cells from Aβ m...

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Detalles Bibliográficos
Autores principales: Cameron, Ryan T., Quinn, Steven D., Cairns, Lynn S., MacLeod, Ruth, Samuel, Ifor D.W., Smith, Brian O., Carlos Penedo, J., Baillie, George S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148482/
https://www.ncbi.nlm.nih.gov/pubmed/24859569
http://dx.doi.org/10.1016/j.mcn.2014.05.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148482/
https://www.ncbi.nlm.nih.gov/pubmed/24859569
http://dx.doi.org/10.1016/j.mcn.2014.05.002

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