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The phosphorylation of Hsp20 enhances its association with amyloid-β to increase protection against neuronal cell death
Up-regulation of Hsp20 protein levels in response to amyloid fibril formation is considered a key protective response against the onset of Alzheimer's disease (AD). Indeed, the physical interaction between Hsp20 and Aβ is known to prevent Aβ oligomerisation and protects neuronal cells from Aβ m...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148482/ https://www.ncbi.nlm.nih.gov/pubmed/24859569 http://dx.doi.org/10.1016/j.mcn.2014.05.002 |