Phenethyl isothiocyanate upregulates death receptors 4 and 5 and inhibits proliferation in human cancer stem-like cells

BACKGROUND: The cytokine TRAIL (tumor necrotic factor-related apoptosis-inducing ligand) selectively induces apoptosis in cancer cells, but cancer stem cells (CSCs) that contribute to cancer-recurrence are frequently TRAIL-resistant. Here we examined hitherto unknown effects of the dietary anti-carc...

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Detalles Bibliográficos
Autores principales: Wang, Dan, Upadhyaya, Bijaya, Liu, Yi, Knudsen, David, Dey, Moul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148558/
https://www.ncbi.nlm.nih.gov/pubmed/25127663
http://dx.doi.org/10.1186/1471-2407-14-591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148558/
https://www.ncbi.nlm.nih.gov/pubmed/25127663
http://dx.doi.org/10.1186/1471-2407-14-591

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