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Unraveling the Convoluted Biological Roles of Type I Interferons in Infection and Immunity: A Way Forward for Therapeutics and Vaccine Design

It has been well-established that type I interferons (IFN-Is) have pleiotropic effects and play an early central role in the control of many acute viral infections. However, their pleiotropic effects are not always beneficial to the host and in fact several reports suggest that the induction of IFN-...

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Detalles Bibliográficos
Autores principales: Wijesundara, Danushka Kumara, Xi, Yang, Ranasinghe, Charani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148647/
https://www.ncbi.nlm.nih.gov/pubmed/25221557
http://dx.doi.org/10.3389/fimmu.2014.00412