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A cellular genetics approach identifies gene-drug interactions and pinpoints drug toxicity pathway nodes

New approaches to toxicity testing have incorporated high-throughput screening across a broad-range of in vitro assays to identify potential key events in response to chemical or drug treatment. To date, these approaches have primarily utilized repurposed drug discovery assays. In this study, we des...

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Detalles Bibliográficos
Autores principales: Suzuki, Oscar T., Frick, Amber, Parks, Bethany B., Trask, O. Joseph, Butz, Natasha, Steffy, Brian, Chan, Emmanuel, Scoville, David K., Healy, Eric, Benton, Cristina, McQuaid, Patricia E., Thomas, Russell S., Wiltshire, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148776/
https://www.ncbi.nlm.nih.gov/pubmed/25221565
http://dx.doi.org/10.3389/fgene.2014.00272